| Champ: |  Arantxa Sánchez Vicario |
| Runner: | Steffi Graf |
| Score: | 6–4, 3–6, 6–3 |
| Draw: | 96 |
| Seeds: | 32 |
| Main Name: | Miami Open (tennis) Miami Open |
| Before Name: | Lipton International Players Championships |
| After Name: | Lipton Championships |
See main article: 1993 Lipton Championships.
Defending champion Arantxa Sánchez Vicario defeated Steffi Graf in the final, 6–4, 3–6, 6–3 to win the women's singles tennis title at the 1993 Miami Open.[1]
All seeds receive a bye into the second round.