See main article: article and 1992 US Open (tennis).
Manon Bollegraf and Tom Nijssen were the defending champions but only Nijssen competed that year with Helena Suková.
Suková and Nijssen lost in the final 4–6, 6–3, 6–3 against Nicole Provis and Mark Woodforde.
Champion seeds are indicated in bold text while text in italics indicates the round in which those seeds were eliminated.