See main article: 1992 Australian Open.
Defending champion Monica Seles defeated Mary Joe Fernández in the final, 6–2, 6–3 to win the women's singles tennis title at the 1992 Australian Open.
The seeded players are listed below. Monica Seles is the champion; others show the round in which they were eliminated.
See main article: 1992 Australian Open – Women's singles qualifying.