The 1992–93 season was the 78th season of the Isthmian League, which is an English football competition featuring semi-professional and amateur clubs from London, East and South East England. League consisted of four divisions.
| Competition: | Isthmian League Premier Division |
| Season: | 1992–93 |
| Winners: | Chesham United |
| Promoted: | None |
| Relegated: | Bognor Regis Town Staines Town Windsor & Eton |
| Matches: | 462 |
| Total Goals: | 1428 |
| Highest Attendance: | 3,120 – St Albans City – Chesham United, (13 February) |
| Attendance: | 212,741 |
| Average Attendance: | 461 (-9.2% to previous season) |
| Prevseason: | 1991–92 |
| Nextseason: | 1993–94 |
The Premier Division consisted of 22 clubs, including 19 clubs from the previous season and three clubs promoted from Division One:
No teams were promoted this year after Chesham United and St Albans City were denied due to ground grading.
| Competition: | Isthmian League Division One |
| Season: | 1992–93 |
| Winners: | Hitchin Town |
| Promoted: | Dorking Hitchin Town Molesey |
| Relegated: | Lewes Aveley |
| Matches: | 420 |
| Total Goals: | 1181 |
| Highest Attendance: | 804 – Hitchin Town – Uxbridge, (1 May) |
| Attendance: | 68,130 |
| Average Attendance: | 162 (-5.3% to previous season) |
| Prevseason: | 1991–92 |
| Nextseason: | 1993–94 |
Division One consisted of 21 clubs, including 17 clubs from the previous season and four new clubs:
Before the start of the season Leyton-Wingate changed name to Leyton.
| Competition: | Isthmian League Division Two |
| Season: | 1992–93 |
| Winners: | Worthing |
| Promoted: | Berkhamsted Town Ruislip Manor Worthing |
| Relegated: | Harefield United Southall |
| Matches: | 462 |
| Total Goals: | 1432 |
| Highest Attendance: | 1,130 – Hemel Hempstead – Berkhamsted Town, (12 April) |
| Attendance: | 57,883 |
| Average Attendance: | 125 (+9.6% to previous season) |
| Prevseason: | 1991–92 |
| Nextseason: | 1993–94 |
Division Two consisted of 22 clubs, including 18 clubs from the previous season and four clubs promoted from Division Three:
| Competition: | Isthmian League Division Three |
| Season: | 1992–93 |
| Winners: | Aldershot Town |
| Promoted: | Aldershot Town Collier Row Thame United |
| Matches: | 380 |
| Total Goals: | 1262 |
| Highest Attendance: | 2,923 – Aldershot Town – Collier Row, (23 January) |
| Attendance: | 93,814 |
| Average Attendance: | 247 (+168.5% to previous season) |
| Prevseason: | 1991–92 |
| Nextseason: | 1993–94 |
Division Three consisted of 21 clubs, including 16 clubs from the previous season and five new clubs:
Although, Farnham Town were accepted to the league, club never started the season due to ground grading problems and returned to the Combined Counties League for the 1993–94 season.