| Year: | 1991 |
| Team: | Jackson State Tigers |
| Sport: | football |
| Conference: | Southwestern Athletic Conference |
| Short Conf: | SWAC |
| Record: | 5–5 |
| Conf Record: | 3–4 |
| Head Coach: | W. C. Gorden |
| Hc Year: | 16th |
| Stadium: | Mississippi Veterans Memorial Stadium |
The 1991 Jackson State Tigers football team represented Jackson State University as a member of the Southwestern Athletic Conference (SWAC) during the 1991 NCAA Division I-AA football season. Led by 16th-year head coach W. C. Gorden, the Tigers compiled an overall record of 5–5 and a mark of 3–4 in conference play, and finished tied for sixth in the SWAC.
The following Tigers were selected in the 1992 NFL draft after the season.[1]
| 2 | 36 | Jimmy Smith | Wide receiver | Dallas Cowboys | |
| 8 | 208 | Dietrich Lockridge | Guard | Denver Broncos |