| Year: | 1991 |
| Team: | Clemson Tigers |
| Conference: | Atlantic Coast Conference |
| Short Conf: | ACC |
| Coachrank: | 17 |
| Aprank: | 18 |
| Record: | 9–2–1 |
| Conf Record: | 6–0–1 |
| Head Coach: | Ken Hatfield |
| Hc Year: | 2nd |
| Off Coach: | Larry Van Der Hayden |
| Oc Year: | 2nd |
| Def Coach: | Ron Dickerson |
| Dc Year: | 1st |
| Captain: | Rob Bodine |
| Captain2: | DeChane Cameron |
| Captain3: | Levon Kirkland |
| Stadium: | Memorial Stadium |
| Champion: | ACC champion |
| Bowl: | Florida Citrus Bowl |
| Bowl Result: | L 13–37 vs. California |
The 1991 Clemson Tigers football team represented Clemson University as a member of the Atlantic Coast Conference (ACC) during the 1991 NCAA Division I-A football season. Led by second-year head coach Ken Hatfield, the Tigers compiled an overall record of 9–2–1 with a mark of 6–0–1 in conference play, winning the ACC title. Clemson was invited to the Florida Citrus Bowl, where the Tigers lost to California. The team played home games at Memorial Stadium in Clemson, South Carolina.
The following Tigers were selected in the 1992 NFL draft after the season.[1]
| 1 | 16 | Chester McGlockton | Defensive tackle | Los Angeles Raiders | |
| 2 | 38 | Levon Kirkland | Linebacker | Pittsburgh Steelers | |
| 5 | 117 | Curtis Whitley | Center | San Diego Chargers | |
| 5 | 125 | Ed McDaniel | Linebacker | Minnesota Vikings |