| Competition: | Serie B |
| Season: | 1991–92 |
| Promoted: | Brescia (2nd title) Pescara Ancona Udinese |
| Relegated: | Casertana Palermo Messina Avellino |
| League Topscorer: | Maurizio Ganz (19 goals) |
| Matches: | 380 |
| Total Goals: | 740 |
| Prevseason: | 1990–91 |
| Nextseason: | 1992–93 |
The Serie B 1991–92 was the sixtieth tournament of this competition played in Italy since its creation.
Piacenza, Venezia, Casertana and Palermo had been promoted from Serie C, while Lecce, Pisa, Cesena and Bologna had been relegated from Serie A.
Casertana relegated to Serie C1.