See main article: 1990 US Open (tennis).
Pete Sampras defeated Andre Agassi in the final, 6–4, 6–3, 6–2 to win the men's singles tennis title at the 1990 US Open. It was his first major title, and the first of a then-record 14 men's singles major titles overall.
Boris Becker was the defending champion, but lost to Agassi in the semifinals.
Sampras defeated Ivan Lendl in the quarterfinals, ending Lendl's record streak of eight consecutive men's finals appearances at the US Open.
The seeded players are listed below. Pete Sampras is the champion; others show the round in which they were eliminated.
Stefan Edberg (first round)
Andre Agassi (finalist)
Andrés Gómez (first round)
Thomas Muster (fourth round)
Emilio Sánchez (fourth round) Brad Gilbert (third round) Aaron Krickstein (quarterfinalist) Michael Chang (third round) Pete Sampras (champion) Jay Berger (fourth round) Jim Courier (second round)
Martín Jaite (second round)