| Season: | 1990–91 |
| League Topscorer: | Gianluca Vialli (19) |
| Season Topscorer: | Gianluca Vialli (23) |
| Cup3 Result: | Runners-up |
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| Nextseason: | 1991–92 |
U.C. Sampdoria won their first ever Serie A title, thanks to a remarkable season for a team playing at its absolute peak. Gianluca Vialli was the league top scorer on 19 goals, and Roberto Mancini, Attilio Lombardo, goalkeeper Gianluca Pagliuca plus centre half Pietro Vierchowod were also instrumental in Sampdoria's success story.
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Gianluca Vialli 19 Roberto Mancini 12 Marco Branca 5
Toninho Cerezo 3 Attilio Lombardo 3 Pietro Vierchowod 3See main article: 1990–91 Coppa Italia. Second roundThird roundQuarterfinalsSemifinalsFinal
See main article: 1991 Coppa Italia Final.
See main article: 1990–91 European Cup Winners' Cup. Round of 16EightfinalsQuarterfinals
See main article: 1990 European Super Cup.