| Election Name: | 1988 United States Senate election in West Virginia |
| Country: | West Virginia |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1982 United States Senate election in West Virginia |
| Previous Year: | 1982 |
| Next Election: | 1994 United States Senate election in West Virginia |
| Next Year: | 1994 |
| Election Date: | November 8, 1988 |
| Image1: | Robert Byrd official portrait (cropped).jpg |
| Nominee1: | Robert Byrd |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 410,983 |
| Percentage1: | 64.77% |
| Nominee2: | Jay Wolfe |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 223,564 |
| Percentage2: | 35.23% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | Robert Byrd |
| Before Party: | Democratic Party (United States) |
| After Election: | Robert Byrd |
| After Party: | Democratic Party (United States) |
The 1988 United States Senate election in West Virginia took place on November 8, 1988. Incumbent Democratic U.S. Senator Robert Byrd won re-election to a sixth term.