| Flag Image: | Flag of San Juan, Puerto Rico.svg |
| Country: | Puerto Rico |
| Type: | presidential |
| Previous Election: | 1984 San Juan, Puerto Rico, mayoral election |
| Previous Year: | 1984 |
| Next Election: | 1992 San Juan, Puerto Rico, mayoral election |
| Next Year: | 1992 |
| Election Date: | November 2, 1988 |
| Image1: | HectorLuisAcevedo2005nyc (1).jpg |
| Nominee1: | Héctor Luis Acevedo |
| Party1: | Popular Democratic Party (Puerto Rico) |
| Popular Vote1: | 100,525 |
| Nominee2: | José Granados |
| Party2: | New Progressive Party (Puerto Rico) |
| Popular Vote2: | 100,496 |
| Mayor | |
| Before Election: | Baltasar Corrada del Río |
| Before Party: | New Progressive Party (Puerto Rico) |
| After Election: | Héctor Luis Acevedo |
| After Party: | Popular Democratic Party (Puerto Rico) |
San Juan, Puerto Rico, held an election for mayor on November 2, 1988. It was held as part of the 1988 Puerto Rican general election. It saw the election Héctor Luis Acevedo, a member of the Popular Democratic Party. Acevedo defeated his main opponent, New Progressive Party nominee José Granados (the minority leader of the Puerto Rico House of Representatives) by margin of merely 29 votes (winning 100,525 votes to Granados' 100,496 votes). Acevedo became the first Popular Democratic Party mayor in twenty years, ending a twenty-year long streak of New Progressive Party mayors.[1]
Incumbent mayor Baltasar Corrada del Río did not seek reelection, instead running unsuccessfully for governor.
The election coincided with a landslide success that year for the Popular Democratic Party.