| Grand Prix: | Nations |
| Flag: | Italy |
| Official Name: | Gran Premio d'Italia |
| Location: | Autodromo Dino Ferrari |
| Course Mi: | 3.132 |
| Course Km: | 5.040 |
| Race No: | 5 |
| Season No: | 15 |
| Date: | 22 May |
| Year: | 1988 |
| Pole Rider 500: | Wayne Gardner |
| Pole Rider 500 Country: | Australia |
| Pole Rider 500 Bike: | Honda |
| Pole Time 500: | 1:55.030 |
| Fast Rider 500: | Eddie Lawson |
| Fast Rider 500 Country: | USA |
| Fast Rider 500 Bike: | Yamaha |
| Fast Time 500: | 1:54.410 |
| First Rider 500: | Eddie Lawson |
| First Rider 500 Country: | USA |
| First Rider 500 Bike: | Yamaha |
| Second Rider 500: | Wayne Gardner |
| Second Rider 500 Country: | Australia |
| Second Rider 500 Bike: | Honda |
| Third Rider 500: | Wayne Rainey |
| Third Rider 500 Country: | USA |
| Third Rider 500 Bike: | Yamaha |
| Pole Rider 250: | Dominique Sarron |
| Pole Rider 250 Country: | France |
| Pole Rider 250 Bike: | Honda |
| Pole Time 250: | 1:59.990 |
| Fast Rider 250: | Dominique Sarron |
| Fast Rider 250 Country: | France |
| Fast Rider 250 Bike: | Honda |
| First Rider 250: | Dominique Sarron |
| First Rider 250 Country: | France |
| First Rider 250 Bike: | Honda |
| Second Rider 250: | Sito Pons |
| Second Rider 250 Country: | Spain |
| Second Rider 250 Bike: | Honda |
| Third Rider 250: | Juan Garriga |
| Third Rider 250 Country: | Spain |
| Third Rider 250 Bike: | Yamaha |
| Pole Rider 125: | Jorge Martínez |
| Pole Rider 125 Country: | Spain |
| Pole Rider 125 Bike: | Derbi |
| Pole Time 125: | 2:08.140 |
| Fast Rider 125: | Jorge Martínez |
| Fast Rider 125 Country: | Spain |
| Fast Rider 125 Bike: | Derbi |
| First Rider 125: | Jorge Martínez |
| First Rider 125 Country: | Spain |
| First Rider 125 Bike: | Derbi |
| Second Rider 125: | Manuel Herreros |
| Second Rider 125 Country: | Spain |
| Second Rider 125 Bike: | Derbi |
| Third Rider 125: | Ezio Gianola |
| Third Rider 125 Country: | Italy |
| Third Rider 125 Bike: | Honda |
| Pole Rider 80: | Jorge Martínez |
| Pole Rider 80 Country: | Spain |
| Pole Rider 80 Bike: | Derbi |
| Pole Time 80: | 2:12.000 |
| Fast Rider 80: | Jorge Martínez |
| Fast Rider 80 Country: | Spain |
| Fast Rider 80 Bike: | Derbi |
| First Rider 80: | Jorge Martínez |
| First Rider 80 Country: | Spain |
| First Rider 80 Bike: | Derbi |
| Second Rider 80: | Stefan Dörflinger |
| Second Rider 80 Country: | Switzerland |
| Second Rider 80 Bike: | Krauser |
| Third Rider 80: | Manuel Herreros |
| Third Rider 80 Country: | Spain |
| Third Rider 80 Bike: | Derbi |
The 1988 Nations motorcycle Grand Prix was the fifth race of the 1988 Grand Prix motorcycle racing season. It took place on the weekend of 20–22 May 1988, at the Autodromo Dino Ferrari.
Wayne Gardner on pole. Through the first turn, it was Eddie Lawson, Kevin Schwantz, Didier De Radiguès, Pierfrancesco Chili and Gardner.
At the end of the first lap, it was Lawson, De Radiguès, Schwantz, Gardner, Chili and Wayne Rainey.
Another few laps and it was Lawson, Gardner, De Radiguès, then a small gap to Rainey and Schwantz.
Lawson got a gap from a re-formed quartet behind. Christian Sarron went down at a chicane, forcing Kevin Magee and Niall Mackenzie off the track.
On the cool down lap there was a collision between Tadahiko Taira and Raymond Roche.
| Pos. | Rider | Team | Manufacturer | Time/Retired | Points | |||
|---|---|---|---|---|---|---|---|---|
| 1 |  Eddie Lawson | Marlboro Yamaha Team Agostini | Yamaha | 48:17.160 | 20 | |||
| 2 |  Wayne Gardner | Rothmans Honda Team | Honda | +15.510 | 17 | |||
| 3 | Wayne Rainey | Team Lucky Strike Roberts | Yamaha | +26.740 | 15 | |||
| 4 | Kevin Schwantz | Suzuki Pepsi Cola | Suzuki | +32.860 | 13 | |||
| 5 | Kevin Magee | Team Lucky Strike Roberts | Yamaha | +48.490 | 11 | |||
| 6 |  Pierfrancesco Chili | HB Honda Gallina Team | Honda | +53.120 | 10 | |||
| 7 | Randy Mamola | Cagiva Corse | Cagiva | +1:15.110 | 9 | |||
| 8 |  Shunji Yatsushiro | Rothmans Honda Team | Honda | +1:16.770 | 8 | |||
| 9 |  Raymond Roche | Cagiva Corse | Cagiva | +1:17.210 | 7 | |||
| 10 | Tadahiko Taira | Tech 21 | Yamaha | +1:18.010 | 6 | |||
| 11 |  Niall Mackenzie | Team HRC | Honda | +1 Lap | 5 | |||
| 12 | Rob McElnea | Suzuki Pepsi Cola | Suzuki | +1 Lap | 4 | |||
| 13 | Alessandro Valesi | Team Iberia | Honda | +1 Lap | 3 | |||
| 14 |  Marco Gentile | Fior Marlboro | Fior | +1 Lap | 2 | |||
| 15 | Patrick Igoa | Sonauto Gauloises Blondes Yamaha Mobil 1 | Yamaha | +1 Lap | 1 | |||
| 16 | Ron Haslam | Team ROC Elf Honda | Elf Honda | +1 Lap | ||||
| 17 | Alberto Rota | Honda | +1 Lap | |||||
| 18 |  Fabio Barchitta | Racing Team Katayama | Honda | +1 Lap | ||||
| 19 | Bruno Kneubühler | Romer Racing Suisse | Honda | +1 Lap | ||||
| 20 | Romolo Balbi | Honda | +1 Lap | |||||
| 21 |  Ari Ramo | Honda | +1 Lap | |||||
| 22 |  Peter Sköld | Team Honda Sweden | Honda | +1 Lap | ||||
| 23 | Rachel Nicotte | PVI Racing | Honda | +1 Lap | ||||
| 24 | Marco Papa | Team Greco | Honda | +1 Lap | ||||
| 25 |  Maarten Duyzers | HDJ International | Honda | +1 Lap | ||||
| 26 | Nicholas Schmassman | FMS | Honda | +1 Lap | ||||
| Ret | Steve Manley | Gateford Motors | Suzuki | Retirement | ||||
| Ret |  Manfred Fischer | Team Hein Gericke | Honda | Retirement | ||||
| Ret |  Daniel Amatriain | Ducados Lotus Guarz | Honda | Retirement | ||||
| Ret | Christian Sarron | Sonauto Gauloises Blondes Yamaha Mobil 1 | Yamaha | Retirement | ||||
| Ret | Massimo Broccoli | Cagiva Corse | Cagiva | Retirement | ||||
| Ret | Roger Burnett | Racing Team Katayama | Honda | Retirement | ||||
| Ret |  Didier de Radiguès | Marlboro Yamaha Team Agostini | Yamaha | Retirement | ||||
| Ret | Jean Luc Demierre | Suzuki | Retirement | |||||
| Ret | Vittorio Scatola | Road Racing Team Avia | Paton | Retirement | ||||
| Ret | Fabio Biliotti | Team Amoranto | Honda | Retirement | ||||
| DNQ |  Andreas Leuthe | Suzuki | Did not qualify | |||||
| DNQ |  Larry Moreno Vacondio | Suzuki | Did not qualify | |||||
| DNQ | Leandro Becheroni | Honda | Did not qualify | |||||
| Sources: [1] [2] | ||||||||