| Year: | 1988 |
| Team: | Eastern Kentucky Colonels |
| Sport: | football |
| Conference: | Ohio Valley Conference |
| Short Conf: | OVC |
| Record: | 11–3 |
| Conf Record: | 6–0 |
| Head Coach: | Roy Kidd |
| Hc Year: | 25th |
| Stadium: | Hanger Field |
| Champion: | OVC champion |
| Bowl: | NCAA Division I-AA Semifinal |
| Bowl Result: | L 17–21 at Georgia Southern |
The 1988 Eastern Kentucky Colonels football team represented Eastern Kentucky University as a member of the Ohio Valley Conference (OVC) during the 1988 NCAA Division I-AA football season. Led by 25th-year head coach Roy Kidd, the Colonels compiled an overall record of 11–3, with a mark of 6–0 in conference play, and finished as OVC champion. Eastern Kentucky advanced to the NCAA Division I-AA Semifinal and were defeated by Georgia Southern.