| Year: | 1988 |
| Team: | Duke Blue Devils |
| Sport: | football |
| Conference: | Atlantic Coast Conference |
| Short Conf: | ACC |
| Record: | 7–3–1 |
| Conf Record: | 3–3–1 |
| Head Coach: | Steve Spurrier |
| Hc Year: | 2nd |
| Def Coach: | Rick Johnson |
| Dc Year: | 1st |
| Mvp: | Anthony Dilweg |
| Captain: | Wayne Charles, Anthony Dilweg, Jeff Patten |
| Stadium: | Wallace Wade Stadium |
The 1988 Duke Blue Devils football team represented Duke University as a member of the Atlantic Coast Conference (ACC) during the 1988 NCAA Division I-A football season. Led by second-year head coach Steve Spurrier, the Blue Devils compiled an overall record of 7–3–1 with a mark of 3–3–1 in conference play, and finished sixth in the ACC. Duke played home games at Wallace Wade Stadium in Durham, North Carolina.