| Champ: |  Javier Sánchez |
| Runner: |  Guillermo Pérez Roldán |
| Score: | 6–2, 7–6 |
| Draw: | 32 |
| Seeds: | 8 |
| Type: | singles doubles |
| After Year: | 1993 |
| After Name: | ATP Buenos Aires |
See main article: 1988 Buenos Aires Grand Prix (tennis).
Javier Sánchez defeated Guillermo Pérez Roldán 6–2, 7–6 to win the 1988 Buenos Aires Grand Prix singles competition. Perez-Roldan was the defending champion.
Guillermo Pérez Roldán (final)
Jay Berger (quarterfinals) Alberto Mancini (semifinals) Horacio de la Peña (second round) Eduardo Bengoechea (quarterfinals) Franco Davín (first round) Javier Sánchez (champion)
Raúl Viver (first round)