| Coppa Italia | |
| Year: | 1988–89 |
| Num Teams: | 48 |
| Winners: | Sampdoria |
| Count: | 3 |
| Second: | Napoli |
| Matches: | 170 |
| Goals: | 447 |
| Scoring Leader: | Gianluca Vialli (13 goals) |
| Prev Season: | 1987–88 |
| Next Season: | 1989–90 |
The 1988–89 Coppa Italia was the 42nd Coppa Italia, the major Italian domestic cup. The competition was won by Sampdoria, who defeated Napoli 4–1 on aggregate in a two-legged final played at Stadio San Paolo (Napoli's home venue) and Stadio Giovanni Zini (neutral venue due to unavailability of Sampdoria's Stadio Luigi Ferraris home venue).
| Atalanta | 4-3 | Lazio | 2-0 | 2-3 | |
| Napoli | 4-3 | Ascoli | 3-0 | 1-3 | |
| Sampdoria | 4-1 | Fiorentina | 3-0 | 1-1 | |
| Hellas Verona | 2-2 (a) | Pisa | 2-1 | 0-1 |
| Atalanta | 3-6 | Sampdoria | 2-3 | 1-3 | |
| Pisa | 0-3 | Napoli | 0-2 | 0-1 |
See main article: 1989 Coppa Italia final.
Sampdoria won 4–1 on aggregate.
