The 1988–89 Midland Football Combination season was the 52nd in the history of Midland Football Combination, a football competition in England.
| Competition: | Midland Football Combination Premier Division |
| Season: | 1988–89 |
| Winners: | Boldmere St. Michaels |
| Promoted: | Racing Club Warwick |
| Relegated: | Shirley Town |
| Matches: | 306 |
| Total Goals: | 933 |
| Prevseason: | 1987–88 |
| Nextseason: | 1989–90 |
The Premier Division featured 15 clubs which competed in the division last season, along with three new clubs: