The 1985–86 Midland Football Combination season was the 49th in the history of Midland Football Combination, a football competition in England.
| Competition: | Midland Football Combination Premier Division |
| Season: | 1985–86 |
| Winners: | Boldmere St. Michaels |
| Matches: | 380 |
| Total Goals: | 1100 |
| Prevseason: | 1984–85 |
| Nextseason: | 1986–87 |
The Premier Division featured 19 clubs which competed in the division last season along with one new club, promoted from Division One: