| Year: | 1981 |
| Team: | Southern Miss Golden Eagles |
| Sport: | football |
| Conference: | Independent |
| Coachrank: | 19 |
| Record: | 9–2–1 |
| Head Coach: | Bobby Collins |
| Hc Year: | 7th |
| Stadium: | M. M. Roberts Stadium |
| Bowl: | Tangerine Bowl |
| Bowl Result: | L 17–19 vs. Missouri |
The 1981 Southern Miss Golden Eagles football team was an American football team that represented the University of Southern Mississippi as an independent during the 1981 NCAA Division I-A football season. In their seventh year under head coach Bobby Collins, the team compiled a 9–2–1 record.[1]