| Champ: |  Kathy Jordan Paula Smith |
| Runner: | JoAnne Russell Virginia Ruzici |
| Score: | 6–3, 5–7, 7–6 |
| Type: | women |
| Draw: | 28 |
| Seeds: | 7 |
| Before Name: | Murjani WTA Championships |
| After Name: | Murjani WTA Championships |
| Main Name: | Amelia Island Championships |
See main article: article and 1981 Murjani WTA Championships.
Rosemary Casals and Ilana Kloss were the defending champions, but Kloss did not compete this year. Casals teamed up with Wendy Turnbull and lost in semifinals to Kathy Jordan and Paula Smith.
Kathy Jordan and Paula Smith won the title by defeating JoAnne Russell and Virginia Ruzici 6–3, 5–7, 7–6 in the final.
The first four seeds received a bye into the second round.