| Year: | 1981 |
| Team: | Middle Tennessee Blue Raiders |
| Sport: | football |
| Conference: | Ohio Valley Conference |
| Short Conf: | OVC |
| Record: | 6–5 |
| Conf Record: | 4–4 |
| Head Coach: | Boots Donnelly |
| Hc Year: | 3rd |
| Stadium: | Johnny "Red" Floyd Stadium |
The 1981 Middle Tennessee Blue Raiders football team represented Middle Tennessee State University in the 1981 NCAA Division I-AA football season. Th team finished with a 6–5 record, 4–4 (tied for fourth) in the Ohio Valley Conference.