| Tourney Name: | Copa Fraternidad |
| Year: | 1981 |
| Num Teams: | 12 |
| Associations: | 3 |
| Champion Other: | Real España |
| Count: | 1 |
| Second Other: | Olimpia Marathón |
| Prevseason: | 1980 |
| Nextseason: | 1982 |
The 1981 Copa Fraternidad was the 11th edition of the Central American football club championship organized by UNCAF, the regional governing body of Central America.
Real España won their first title by winning the final round, as Olimpia and Marathón quit the tournament.[1]
Only El Salvador, Guatemala and Honduras sent representatives.
| Association | Team | Qualifying method | Previous best | |
|---|---|---|---|---|
| 1980–81 Champions | 5th | 4th (1971) | ||
| 1980–81 Runners-up | 3rd | First Round (1979, 1980) | ||
| 1980–81 Third place | 7th | Runners-up (1980) | ||
| 1980–81 Fourth place | 6th | Runners-up (1973) | ||
| 1980 Champions | 1st | — | ||
| 1980 Runners-up | 1st | — | ||
| 1980 Third place | 9th | Champions (1971) | ||
| 1980 Fourth place | 2nd | First Round (1980) | ||
| 1980–81 Champions | 2nd | Runners-up (1979) | ||
| 1980–81 Runners-up | 2nd | First Round (1980) | ||
| 1980–81 Third place | 2nd | Group stage (1979) | ||
| 1980–81 Fourth place | 1st | — |
|}
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