| Competition: | Alpha Ethniki |
| Season: | 1981–82 |
| Winners: | Olympiacos 23rd Greek title |
| Relegated: | Kavala Korinthos |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | Olympiacos |
| Continentalcup2: | Cup Winners' Cup |
| Continentalcup2 Qualifiers: | Panathinaikos |
| Continentalcup3: | UEFA Cup |
| Continentalcup3 Qualifiers: | AEK Athens PAOK |
| League Topscorer: | Grigoris Charalampidis (21 goals) |
| Matches: | 306 |
| Total Goals: | 709 |
| Prevseason: | 1980–81 |
| Nextseason: | 1982–83 |
The 1981–82 Alpha Ethniki was the 46th season of the highest football league of Greece. The season began on 6 September 1981 and ended on 30 May 1982. Olympiacos won their third consecutive and 23rd Greek title.
The point system was: Win: 2 points - Draw: 1 point.
| Rank | Player | Club | Goals | |
|---|---|---|---|---|
| 1 | Grigoris Charalampidis | Panathinaikos | 21 | |
| 2 | Georgios Kostikos | PAOK | 18 | |
| 3 | Thomas Mavros | AEK Athens | 17 | |
| 4 | Dinos Kouis | Aris | 15 | |
| 5 | Thomas Liolios | Kastoria | 14 | |
| 6 | Nikos Anastopoulos | Olympiacos | 13 | |
| Giorgos Zindros | Aris | |||
| Giorgos Kalambakas | Iraklis | |||
| Dimitris Saravakos | Panionios | |||
| 10 | Vasilis Papadimitriou | Panserraikos | 11 |