| Season: | –82 |
| Competition: | Serie A |
| Dates: | 13 September 1981 – 16 May 1982 |
| Winners: | Juventus (20th title) |
| Relegated: | Milan Bologna Como |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | Juventus |
| Continentalcup3: | UEFA Cup |
| Continentalcup3 Qualifiers: | Roma Fiorentina Napoli |
| Continentalcup2: | Cup Winners' Cup |
| Continentalcup2 Qualifiers: | Internazionale |
| Matches: | 240 |
| Total Goals: | 474 |
| League Topscorer: | Roberto Pruzzo (15 goals) |
| Prevseason: | 1980–81 |
| Nextseason: | 1982–83 |
The 1981–82 Serie A season was won by Juventus.
Milan, Cesena and Genoa had been promoted from Serie B.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Roberto Pruzzo | Roma | 15 |
| 2 | Edi Bivi | Catanzaro | 12 |
| 3 | Claudio Pellegrini | Napoli | 11 |
| 4 |  Daniel Bertoni | Fiorentina | 9 |
| Francesco Graziani | Fiorentina | ||
 Walter Schachner | Cesena | ||
| Oliviero Garlini | Cesena | ||
| Roberto Mancini | Bologna | ||
| Pietro Paolo Virdis | Juventus | ||
| Alessandro Altobelli | Internazionale | ||
| Evaristo Beccalossi | Internazionale | ||
| Luigi Piras | Cagliari |