| Year: | 1980 |
| Team: | Vanderbilt Commodores |
| Sport: | football |
| Conference: | Southeastern Conference |
| Short Conf: | SEC |
| Record: | 2–9 |
| Conf Record: | 0–6 |
| Hc Year: | 2nd |
| Off Coach: | Red Parker |
| Oc Year: | 1st |
| Def Coach: | Ron McCrone |
| Dc Year: | 2nd |
| Stadium: | Dudley Field |
The 1980 Vanderbilt Commodores football team represented Vanderbilt University in the 1980 NCAA Division I-A football season. The Commodores were led by head coach George MacIntyre in his second season and finished the season with a record of two wins and nine losses (2–9 overall, 0–6 in the SEC).