| Election Name: | 1980 United States Senate election in North Dakota |
| Country: | North Dakota |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1974 United States Senate election in North Dakota |
| Previous Year: | 1974 |
| Next Election: | 1986 United States Senate election in North Dakota |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Image1: | Mark Andrews (cropped).jpg |
| Nominee1: | Mark Andrews |
| Party1: | North Dakota Republican Party |
| Popular Vote1: | 210,347 |
| Percentage1: | 70.29% |
| Nominee2: | Kent Johanneson |
| Party2: | North Dakota Democratic-NPL Party |
| Popular Vote2: | 86,658 |
| Percentage2: | 28.96% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | Milton R. Young |
| Before Party: | North Dakota Republican Party |
| After Election: | Mark Andrews |
| After Party: | North Dakota Republican Party |
The 1980 U.S. Senate election for the state of North Dakota was held November 4, 1980. The incumbent, Republican Senator Milton Young, was retiring. Republican Mark Andrews defeated North Dakota Democratic-NPL Party candidate Kent Johanneson to fill the vacated seat.[1]
Andrews, who had served as a Representative since 1963, easily received the Republican nomination, and the endorsed Democratic-NPL candidate was Kent Johanneson. Andrews and Johanneson won the primary elections for their respective parties.
Two independent candidates, Harley McLain and Don J. Klingensmith also filed before the deadline under the Chemical Farming Banned and Statesman parties respectively. McLain would later run for the same seat in 1998 against then incumbent Byron Dorgan.