See main article: 1980 United States Senate elections.
| Election Name: | 1980 United States Senate election in Maryland |
| Country: | Maryland |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1974 United States Senate election in Maryland |
| Previous Year: | 1974 |
| Next Election: | 1986 United States Senate election in Maryland |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Image1: | File:Charlesmathiasjr (cropped).jpg |
| Nominee1: | Charles Mathias |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 850,970 |
| Percentage1: | 66.17% |
| Nominee2: | Edward T. Conroy |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 435,118 |
| Percentage2: | 33.83% |
| Map Size: | 295px |
| U.S. Senator | |
| Before Election: | Charles Mathias |
| Before Party: | Republican Party (United States) |
| After Election: | Charles Mathias |
| After Party: | Republican Party (United States) |
The 1980 United States Senate election in Maryland took place on November 4, 1980.
Incumbent Republican U.S Senator Charles Mathias won re-election to a third term in a landslide, defeating Democratic State Senator Edward T. Conroy.
As of, this is the last time a Republican won a U.S. Senate election in Maryland. It is also the last time a Republican won Prince George's County and Baltimore City in a statewide election.
| Charlies MathiasRepublican | Edward T. ConroyDemocratic | Margin | TotalVotes Cast | ||||||
|---|---|---|---|---|---|---|---|---|---|
| % | % | % | |||||||
| Allegany | 18,700 | 73.25% | 6,829 | 26.75% | 11,871 | 46.50% | 25,529 | ||
| Anne Arundel | 76,352 | 69.80% | 33,028 | 30.20% | 43,324 | 39.61% | 109,380 | ||
| Baltimore (City) | 108,051 | 56.50% | 83,176 | 43.50% | 24,875 | 13.01% | 191,227 | ||
| Baltimore (County) | 151,087 | 65.75% | 78,694 | 34.25% | 72,393 | 31.51% | 229,781 | ||
| Calvert | 5,774 | 65.10% | 3,096 | 34.90% | 2,678 | 30.19% | 8,870 | ||
| Caroline | 3,586 | 69.54% | 1,571 | 30.46% | 2,015 | 39.07% | 5,157 | ||
| Carroll | 16,623 | 61.78% | 10,285 | 38.22% | 6,338 | 23.55% | 26,908 | ||
| Cecil | 9,507 | 65.08% | 5,101 | 34.92% | 4,406 | 30.16% | 14,608 | ||
| Charles | 11,308 | 63.32% | 6,551 | 36.68% | 4,757 | 26.64% | 17,859 | ||
| Dorchester | 5,463 | 68.43% | 2,520 | 31.57% | 2,943 | 36.87% | 7,983 | ||
| Frederick | 26,230 | 76.31% | 8,143 | 23.69% | 18,087 | 52.62% | 34,373 | ||
| Garrett | 5,136 | 76.15% | 1,609 | 23.85% | 3,527 | 52.29% | 6,745 | ||
| Harford | 32,805 | 72.31% | 12,562 | 27.69% | 20,243 | 44.62% | 45,367 | ||
| Howard | 31,740 | 72.61% | 11,970 | 27.39% | 19,770 | 45.23% | 43,710 | ||
| Kent | 3,331 | 70.13% | 1,419 | 29.87% | 1,912 | 40.25% | 4,750 | ||
| Montgomery | 196,817 | 76.49% | 60,506 | 23.51% | 136,311 | 52.97% | 257,323 | ||
| Prince George's | 87,311 | 52.33% | 79,532 | 47.67% | 7,779 | 4.66% | 166,843 | ||
| Queen Anne's | 4,730 | 68.64% | 2,161 | 31.36% | 2,569 | 37.28% | 6,891 | ||
| St. Mary's | 7,602 | 62.55% | 4,551 | 37.45% | 3,051 | 25.10% | 12,153 | ||
| Somerset | 2,986 | 65.38% | 1,581 | 34.62% | 1,405 | 30.76% | 4,567 | ||
| Talbot | 6,439 | 77.10% | 1,912 | 22.90% | 4,527 | 54.21% | 8,351 | ||
| Washington | 22,460 | 68.73% | 10,220 | 31.27% | 12,240 | 37.45% | 32,680 | ||
| Wicomico | 11,675 | 67.34% | 5,663 | 32.66% | 6,012 | 34.68% | 17,338 | ||
| Worcester | 5,257 | 68.32% | 2,438 | 31.68% | 2,819 | 36.63% | 7,695 | ||
| Total | 850970 | 66.17% | 435,118 | 33.83% | 415,852 | 32.33% | 1,286,088 | ||