| Election Name: | 1980 United States Senate election in Kentucky |
| Country: | Kentucky |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1974 United States Senate election in Kentucky |
| Previous Year: | 1974 |
| Next Election: | 1986 United States Senate election in Kentucky |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Nominee1: | Wendell Ford |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 720,891 |
| Percentage1: | 65.13% |
| Nominee2: | Mary Louise Foust |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 386,029 |
| Percentage2: | 34.87% |
| Map Size: | 300px |
| U.S. Senator | |
| Before Election: | Wendell Ford |
| Before Party: | Democratic Party (United States) |
| After Election: | Wendell Ford |
| After Party: | Democratic Party (United States) |
The 1980 United States Senate election in Kentucky took place on November 4, 1980, concurrently with the U.S. presidential election as well as other elections to the United States Senate in other states as well as other elections to the United States House of Representatives and various state and local elections. Incumbent Democratic Senator Wendell Ford won re-election, defeating Republican nominee Mary Louise Foust.