| Election Name: | 1980 United States Senate election in Hawaii |
| Country: | Hawaii |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1974 United States Senate election in Hawaii |
| Previous Year: | 1974 |
| Next Election: | 1986 United States Senate election in Hawaii |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Image1: | File:Daniel Inouye official photo.jpg |
| Nominee1: | Daniel Inouye |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 224,485 |
| Percentage1: | 77.95% |
| Nominee2: | Cooper Brown |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 53,068 |
| Percentage2: | 18.43% |
| Map Size: | 300px |
| U.S. Senator | |
| Before Election: | Daniel Inouye |
| Before Party: | Democratic Party (United States) |
| After Election: | Daniel Inouye |
| After Party: | Democratic Party (United States) |
The 1980 United States Senate election in Hawaii took place on November 4, 1980.
Incumbent Democratic U.S. Senator Daniel Inouye won re-election to a fourth term in yet another landslide, despite the national 'Reagan Revolution' and the state's very narrow margin of victory for Jimmy Carter in the concurrent presidential election.