| Pbayear: | 1980 |
| Team: | San Miguel Beermen |
| Coach: | Edgardo Ocampo |
| 1C-Name: | Open Conference |
| 1C-Wins: | 4 |
| 1C-Losses: | 14 |
| 1C-Place: | N/A |
| 1C-Playoffs: | N/A |
| 2C-Name: | Invitational Championship |
| 2C-Wins: | 0 |
| 2C-Losses: | 0 |
| 2C-Place: | N/A |
| 2C-Playoffs: | N/A |
| 3C-Name: | All Filipino Conference |
| 3C-Wins: | 5 |
| 3C-Losses: | 9 |
| 3C-Place: | 6th |
| 3C-Playoffs: | Round of six |
| Owners: | San Miguel Corporation |
| Prevseason: | 1979 |
| Nextseason: | 1981 |
The 1980 San Miguel Beermen season was the sixth season of the franchise in the Philippine Basketball Association (PBA). Beginning the Third Conference, the ballclub will be known as San Miguel Beermen, a beer brand long been used by the company in the MICAA will finally makes its debut in the PBA.
The defending champions bring back Otto Moore as their import in the Open Conference along with Bubba Wilson, a one-time backcourt man of the Golden State Warriors in the NBA. The Orangemen lost their first game to U-Tex but pick up their first win of the season four days after against Toyota Tamaraws, 93-84 on March 22. [1] RTO ends up last in the conference and tied with Tanduay at the bottom of the standings after 18 games in the eliminations.
San Miguel advances in the round of six of the All-Filipino Conference and the Beermen lost all their five assignments in the quarterfinal phase of the tournament.
| Teams | Win | Loss | 1st (Open) | 3rd (All-Filipino) | |
| Galleon Shippers | 0 | 3 | 0-2 | 0-1 | |
| Gilbey’s Gin | 2 | 2 | 1-1 | 1-1 | |
| Great Taste / Presto | 1 | 2 | 0-2 | 1-0 | |
| Honda | 2 | 1 | 1-1 | 1-0 | |
| Tanduay | 1 | 3 | 1-1 | 0-2 | |
| Tefilin | 1 | 2 | 0-2 | 1-0 | |
| Toyota Tamaraws | 2 | 2 | 1-1 | 1-1 | |
| U-Tex Wranglers | 0 | 4 | 0-2 | 0-2 | |
| Walk Tall / Crispa | 0 | 4 | 0-2 | 0-2 | |
| Total | 9 | 23 | 4-14 | 5-9 |