| National Challenge Cup | |
| Year: | 1980 |
| Country: | United States |
| Winners: | New York Pancyprian-Freedoms (1st title) |
| Second: | Maccabee A.C. |
| Continental Cup Title: | 1982 CONCACAF Champions' Cup |
| Continental Cup Qualifiers: | New York Pancyprian-Freedoms |
| Prev Season: | 1979 |
| Next Season: | 1981 |
The 1980 National Challenge Cup was the 67th edition of the USSF's annual open soccer championship. Teams from the North American Soccer League declined to participate. New York Pancyprian-Freedoms defeated Maccabee A.C. in the final game. The score was 3–2.[1]