The 1980 Monte Carlo Open was a men's tennis tournament played on outdoor clay courts at the Monte Carlo Country Club in Roquebrune-Cap-Martin, France that was part of the 1980 Volvo Grand Prix circuit. It was the 74th edition of the tournament and was held from 31 March through 6 April 1980. First-seeded Björn Borg won the singles title, his third after 1977 and 1979.
Björn Borg defeated 
Guillermo Vilas 6–1, 6–0, 6–2
Paolo Bertolucci / Adriano Panatta defeated 
Vitas Gerulaitis / John McEnroe 6–2, 5–7, 6–3