| Year: | 1980 |
| Team: | Grambling State Tigers |
| Sport: | football |
| Conference: | Southwestern Athletic Conference |
| Short Conf: | SWAC |
| Record: | 10–2 |
| Conf Record: | 5–1 |
| Head Coach: | Eddie Robinson |
| Hc Year: | 38th |
| Stadium: | Grambling Stadium |
| Champion: | Black college national champion SWAC champion |
| Bowl: | NCAA Division I-AA Semifinal |
| Bowl Result: | L 9–14 at Boise State |
The 1980 Grambling State Tigers football team represented Grambling State University as a member of the Southwestern Athletic Conference (SWAC) during the 1980 NCAA Division I-AA football season. Led by 38th-year head coach Eddie Robinson, the Tigers compiling an overall record of 10–2 and a mark of 5–1 in conference play, and sharing the SWAC title with Jackson State. Grambling State was invited to the NCAA Division I-AA Football Championship playoffs, where they lost to eventual national champion Boise State. The Tigers won a black college football national championship.