| Competition: | Campeonato Profesional |
| Season: | 1980 |
| Winners: | Junior (2nd title) |
| Matches: | 369 |
| Total Goals: | 946 |
| League Topscorer: | Sergio Cierra (26) |
| Prevseason: | 1979 |
| Nextseason: | 1981 |
The 1980 Campeonato Profesional was the thirty-third season of Colombia's top-flight football league. Junior won the league for the second time after winning the Cuadrangular final.[1]