The Campania regional election of 1980 took place on 8 June 1980.
Christian Democracy was by far the largest party, while the Italian Communist Party came distantly second. After the election, Christian Democrat Emilio De Feo was elected President of the Region. In 1983 De Feo was replaced by fellow Christian Democrat Antonio Fantini.
| Parties | votes | votes (%) | seats | |
|---|---|---|---|---|
| Christian Democracy | 1,174,943 | 39.0 | 25 | |
| Italian Communist Party | 726,007 | 24.1 | 15 | |
| Italian Socialist Party | 377,581 | 12.5 | 7 | |
| Italian Social Movement | 339,993 | 11.3 | 7 | |
| Italian Democratic Socialist Party | 187,781 | 6.2 | 3 | |
| Italian Republican Party | 90,206 | 3.0 | 1 | |
| Italian Liberal Party | 51,600 | 1.7 | 1 | |
| Proletarian Democracy | 33,163 | 1.1 | 1 | |
| Proletarian Unity Party | 30,693 | 1.0 | align=right | - |
| Revolutionary Socialist League | 1,651 | 0.1 | align=right | - |
| Total | 3,013,618 | 100.0 | 60 | |