| DFB-Pokal Frauen | |
| Year: | 1980–81 |
| Country: | Germany |
| Num Teams: | 16 |
| Winners: | SSG Bergisch Gladbach |
| Second: | TuS Wörrstadt |
| Matches: | 29 |
| Goals: | 118 |
| Next Season: | 1981–82 |
The Frauen DFB-Pokal 1980–81 was the first season of the cup competition, Germany's second-most important title in women's football.[1] In the final which was held in Stuttgart on 2 June 1981 SSG Bergisch Gladbach defeated TuS Wörrstadt 5–0.[2] The 1980–81 cup was the only cup that was played with each match other than the final going over two legs.
| Northern region | Western region | Southwestern region | Southern region | Berlin | |
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| width=25% | width=10% | width=25% | ||||
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| VfB Komet Bremen | 0 – 14 0 – 7 | BFC Meteor 06 | ||||
| KBC Duisburg | 1 – 1 2 – 1 | VfR Eintracht Wolfsburg | ||||
| SSG Bergisch Gladbach | 3 – 1 2 – 1 | TSV Siegen | ||||
| FV Bellenberg | 4 – 2 1 – 4 | TSV Hungen | ||||
| FC Hellas Marpingen | 0 – 1 0 – 2 | SC 07 Bad Neuenahr | ||||
| SV Schlierstadt | 8 – 1 6 – 0 | VfR Rheinfelden | ||||
| Inter Bergsteig Amberg | 0 – 0 1 – 4 | TuS Wörrstadt | ||||
| TSV Wedel | 1 – 1 1 – 0 | SG Thumby |
| width=25% | width=10% | width=25% | ||||
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| BFC Meteor 06 | 5 – 1 5 – 3 | TSV Wedel | ||||
| KBC Duisburg | 0 – 0 2 – 3 | SSG Bergisch Gladbach | ||||
| TSV Hungen | 1 – 2 1 – 1 | SC 07 Bad Neuenahr | ||||
| SV Schlierstadt | 1 – 2 2 – 3 | TuS Wörrstadt |
| width=25% | width=10% | width=25% | ||||
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| TuS Wörrstadt | 1 – 0 1 – 0 | BFC Meteor 06 | ||||
| SSG Bergisch Gladbach | 6 – 0 3 – 0 | SC 07 Bad Neuenahr |
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