| Algerian Cup | |
| Year: | 1980–81 |
| Other Titles: | كأس الجزائر |
| Defending Champions: | EP Sétif (5) |
| Winners: | USK Alger (1) |
| Second: | ASC Oran |
| Prev Season: | 1979–80 |
| Next Season: | 1981–82 |
The 1980–81 Algerian Cup is the 19th edition of the Algerian Cup. EP Sétif are the defending champions, having beaten USK Alger 1–0 in the previous season's final.