| Competition: | Alpha Ethniki |
| Season: | 1979–80 |
| Winners: | Olympiacos 21st Greek title |
| Relegated: | Iraklis Rodos |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | Olympiacos |
| Continentalcup2: | UEFA Cup |
| Continentalcup2 Qualifiers: | Aris Panathinaikos |
| Continentalcup3: | Cup Winners' Cup |
| Continentalcup3 Qualifiers: | Kastoria |
| League Topscorer: | Dušan Bajević (25 goals) |
| Matches: | 306 |
| Total Goals: | 708 |
| Prevseason: | 1978–79 |
| Nextseason: | 1980–81 |
The 1979–80 Alpha Ethniki was the 44th season of the highest football league of Greece. From that season Alpha Ethniki became the professional league. The season began on 30 September 1979 and ended on 25 May 1980 with the play-off matches. Olympiacos won their 21st Greek title and their first one in five years.
The point system was: Win: 2 points - Draw: 1 point.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | Dušan Bajević | AEK Athens | 25 |
| 2 | Georgios Kostikos | PAOK | 16 |
| Thalis Tsirimokos | PAS Giannina | ||
| 4 | Dimtris Spetzopulos | Panachaiki | 15 |
| 5 | Dimitris Seitaridis | PAS Giannina | 14 |
| Giorgos Kalampakas | Iraklis | ||
| AEK Athens | |||
| Dimitris Pittas | Korinthos | ||
| 9 | Giorgos Pissas | Korinthos | 11 |
| 10 | Maik Galakos | Olympiacos | 10 |
| Dimitris Tsironis | Kastoria | ||
| Christos Yfantidis | Panathinaikos | ||
| Thomas Liolios | Panionios / Kastoria |