| Election Name: | 1978 United States House election in Nevada |
| Country: | Nevada |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1976 United States House of Representatives election in Nevada |
| Previous Year: | 1976 |
| Next Election: | 1980 United States House of Representatives election in Nevada |
| Next Year: | 1980 |
| Election Date: | November 7, 1978 |
| Image1: | Jim Santini.png |
| Nominee1: | Jim Santini |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 132,513 |
| Percentage1: | 69.51% |
| Nominee2: | Bill O'Mara |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 44,425 |
| Percentage2: | 23.30% |
| Map Size: | x240px |
| Representative At-large | |
| Before Election: | James David Santini |
| Before Party: | Democratic Party (United States) |
| After Election: | James David Santini |
| After Party: | Democratic Party (United States) |
The 1978 United States House of Representatives election in Nevada was held on Tuesday November 7, 1978, to elect the state's at-large representative. Primary elections were held on September 12, 1978.
Incumbent representative, James David Santini easily won re-election to a third term. He won every county except for Douglas County with over 60 percent of the vote.