| Year: | 1978 |
| Team: | Grambling State Tigers |
| Sport: | football |
| Conference: | Southwestern Athletic Conference |
| Short Conf: | SWAC |
| Record: | 9–1–1 |
| Conf Record: | 5–0–1 |
| Head Coach: | Eddie Robinson |
| Hc Year: | 36th |
| Stadium: | Grambling Stadium |
| Champion: | SWAC champion |
| Bowl: | Orange Blossom Classic |
| Bowl Result: | L 7–31 vs. Florida A&M |
The 1978 Grambling State Tigers football team represented Grambling State University as a member of the Southwestern Athletic Conference (SWAC) during the 1978 NCAA Division I-AA football season. Led by 36th-year head coach Eddie Robinson, the Tigers compiled an overall record of 9–1–1, with a mark of 5–0–1 in conference play, winning the SWAC title. Grambling State was invited to the Orange Blossom Classic, where they lost to Florida A&M.