| Competition: | Campeonato Profesional |
| Season: | 1978 |
| Winners: | Millonarios (11th title) |
| Matches: | 365 |
| Total Goals: | 974 |
| League Topscorer: | Oswaldo Marcial Palavecino (36) |
| Prevseason: | 1977 |
| Nextseason: | 1979 |
The 1978 Campeonato Profesional was the thirty-first season of Colombia's top-flight football league. Millonarios won the league for the eleventh time after winning the Cuadrangular final.[1]