See main article: 1976 US Open (tennis).
Defending champion Chris Evert defeated Evonne Goolagong in a rematch of the previous year's final, 6–3, 6–0 to win the women's singles tennis title at the 1976 US Open. It was her second US Open title and her sixth major singles title overall. It was Goolagong's fourth consecutive runner-up finish at the event.
The seeded players are listed below. Chris Evert is the champion; others show the round in which they were eliminated.