| Election Name: | 1974 United States Senate election in South Carolina |
| Country: | South Carolina |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1968 United States Senate election in South Carolina |
| Previous Year: | 1968 |
| Next Election: | 1980 United States Senate election in South Carolina |
| Next Year: | 1980 |
| Election Date: | November 5, 1974 |
| Image1: | Ernest Hollings 91st Congress.jpg |
| Nominee1: | Ernest Hollings |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 355,107 |
| Percentage1: | 69.44% |
| Nominee2: | Gwen Bush |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 146,649 |
| Percentage2: | 28.68% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | Ernest Hollings |
| Before Party: | Democratic Party (United States) |
| After Election: | Ernest Hollings |
| After Party: | Democratic Party (United States) |
The 1974 South Carolina United States Senate election was held on November 5, 1974, to select the U.S. Senator from the state of South Carolina. Incumbent Democratic Senator Fritz Hollings easily defeated Republican challenger Gwen Bush to win his third (his second full) term.
Both Fritz Hollings and Gwen Bush faced no opposition in their party's primaries which allowed both candidates to concentrate solely on the general election.
The Watergate scandal caused the Republicans to perform poorly nationwide in 1974 and Gwen Bush was little more than a sacrificial lamb. The main focus of the voters in South Carolina was on the competitive gubernatorial contest and Fritz Hollings easily cruised to a comfortable re-election.
|-| | colspan=5 |Democratic hold|-