See main article: 1973 US Open (tennis).
John Newcombe defeated Jan Kodeš in the final, 6–4, 1–6, 4–6, 6–2, 6–3 to win the men's singles tennis title at the 1973 US Open. It was his second US Open singles title and sixth major singles title overall.
Ilie Năstase was the defending champion, but lost in the second round to Andrew Pattison.
The seeded players are listed below. John Newcombe is the champion; others show the round in which they were eliminated.