| Election Name: | 1972 United States Senate election in Oklahoma |
| Country: | Oklahoma |
| Flag Image: | Flag of Oklahoma (1941–1988).svg |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1966 United States Senate election in Oklahoma |
| Previous Year: | 1966 |
| Next Election: | 1978 United States Senate election in Oklahoma |
| Next Year: | 1978 |
| Election Date: | November 7, 1972 |
| Image1: | Dewey Bartlett.jpg |
| Nominee1: | Dewey F. Bartlett |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 516,934 |
| Percentage1: | 51.43% |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 478,212 |
| Percentage2: | 47.58% |
| Map Size: | 300px |
| U.S. Senator | |
| Before Party: | Democratic Party (US) |
| After Party: | Republican Party (US) |
The 1972 United States Senate election in Oklahoma took place on November 7, 1972. The incumbent Democratic Senator, Fred R. Harris, had retired to run for president.[1] The open seat was won by Republican Dewey F. Bartlett, who defeated Democratic nominee Ed Edmondson. However, his victory underperformed that of President Richard Nixon in the concurrent presidential election, which saw Nixon defeat George McGovern by 49.7% in the state.