| Dates: | 18 March 1972 – 21 December 1972 |
| Winners: | Colo-Colo (11th title) |
| Relegated: | Everton |
| Matches: | 306 |
| Total Goals: | 875 |
| Continentalcup1: | 1973 Copa Libertadores |
| Continentalcup1 Qualifiers: | Colo-Colo Unión Española |
| League Topscorer: | Fernando Espinoza (25 goals) |
| Highest Attendance: | 73,636 |
| Attendance: | 3,617,223 |
| Average Attendance: | 11,821 |
| Prevseason: | 1971 |
| Nextseason: | 1973 |
The 1972 Campeonato Nacional de Fútbol Profesional, was the 40st season of top-flight football in Chile. Colo-Colo won their eleventh title following a 1–1 draw against Huachipato in the championship 33rd matchday on December 16, 1972, also qualifying to the 1973 Copa Libertadores.[1]
| Rank | Name | Club | Goals | ||
|---|---|---|---|---|---|
| align=center | 1 | Fernando Espinoza | Magallanes | 25 | |
| align=center | 2 | Francisco Valdés | Colo-Colo | 23 | |
| align=center | 3 |  Juan Carlos Sarnari | Universidad de Chile | 19 | |
| align=center | 4 | Rogelio Farías | Unión Española | 15 | |
| align=center | 5 | Carlos Caszely | Colo-Colo | 14 |