| Year: | 1972 |
| Team: | Pittsburgh Panthers |
| Sport: | football |
| Conference: | Independent |
| Record: | 1–10 |
| Head Coach: | Carl DePasqua |
| Hc Year: | 4th |
| Off Coach: | Lou Cecconi |
| Oc Year: | 4th |
| Off Scheme: | Wishbone-T |
| Def Coach: | Ralph Jelic |
| Dc Year: | 1st |
| Def Scheme: | 5–2 |
| Stadium: | Pitt Stadium |
The 1972 Pittsburgh Panthers football team represented the University of Pittsburgh in the 1972 NCAA University Division football season.
| Player | Position | Round | Pick | NFL club |
| Ernie Webster | Guard | 12 | 311 | Washington Redskins |
| John Moss | Linebacker | 13 | 331 | Detroit Lions |