| National Challenge Cup | |
| Year: | 1972 |
| Country: |  United States |
| Dates: | 9 January- 21 May 1972 |
| Defending Champions: | New York Hota Bavarian SC |
| Winners: | Elizabeth S.C. |
| Count: | 2 |
| Second: | San Pedro Yugoslavs |
| Semifinal1: | --> |
| Semifinal2: | --> |
| Prev Season: | 1971 |
| Next Season: | 1973 |
The 1972 National Challenge Cup was the 59th edition of the United States Soccer Football Association's annual open soccer championship. Teams from the North American Soccer League declined to participate. Elizabeth S.C. defeated the San Pedro Yugoslavs in the final game.