| Competition: | Alpha Ethniki |
| Season: | 1972–73 |
| Winners: | Olympiacos 18th Greek title |
| Relegated: | Kalamata Atromitos Trikala Omonia |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | Olympiacos |
| Continentalcup2: | Cup Winners' Cup |
| Continentalcup2 Qualifiers: | PAOK |
| Continentalcup3: | UEFA Cup |
| Continentalcup3 Qualifiers: | Panathinaikos Panachaiki |
| League Topscorer: | Antonis Antoniadis (22 goals) |
| Matches: | 306 |
| Total Goals: | 705 |
| Prevseason: | 1971–72 |
| Nextseason: | 1973–74 |
The 1972–73 Alpha Ethniki was the 37th season of the highest football league of Greece. The season began on 17 September 1972 and ended on 3 June 1973. Olympiacos won their 18th Greek title and their first one in six years.
The point system was: Win: 3 points - Draw: 2 points - Loss: 1 point.
| Rank | Player | Club | Goals | |
|---|---|---|---|---|
| 1 | Antonis Antoniadis | Panathinaikos | 22 | |
| 2 | Stavros Sarafis | PAOK | 19 | |
| 3 |  Yves Triantafyllos | Olympiacos | 16 | |
| 4 | Kostas Davourlis | Panachaiki | 15 | |
| Koulis Apostolidis | PAOK | |||
| Andreas Michalopoulos | Panachaiki | |||
| 7 |  Juan Ramón Verón | Panathinaikos | 14 | |
| Giorgos Koudas | PAOK | |||
| 9 | Romain Argyroudis | Olympiacos | 13 |