| Election Name: | 1968 United States Senate election in Indiana |
| Country: | Indiana |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1962 United States Senate election in Indiana |
| Previous Year: | 1962 |
| Next Election: | 1974 United States Senate election in Indiana |
| Next Year: | 1974 |
| Election Date: | November 5, 1968 |
| Image1: | Birch bayh.jpg |
| Nominee1: | Birch Bayh |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 1,060,456 |
| Percentage1: | 51.65% |
| Nominee2: | William Ruckelshaus |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 988,571 |
| Percentage2: | 48.15% |
| Map Size: | 255px |
| U.S. Senator | |
| Before Election: | Birch Bayh |
| Before Party: | Democratic Party (US) |
| After Election: | Birch Bayh |
| After Party: | Democratic Party (US) |
The 1968 United States Senate election in Indiana took place on November 5, 1968. Incumbent Democratic U.S. Senator Birch Bayh was re-elected to a second consecutive term in office, defeating Republican State Representative William Ruckelshaus.